Custom Probe Design

HCR v3.0 probe sets enable multiplexed quantitative RNA fluorescence in situ hybridization (RNA-FISH), RNA flow cytometry, and northern blotting. Learn more 

If your target is not already in our catalog, the Molecular Instruments Team will be pleased to design a custom probe set for any target mRNA in any organism across the tree of life. View gallery

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Custom Ordering

Please provide the accession number (if available) or the target RNA sequence (including 5' and 3' UTRs) when you place the order. 

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Rapid Worldwide Delivery

Upon receipt of a valid purchase order, we aim to ship custom probe sets within 5 business days. 

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Volume Discounts

Volume discounts are available when ordering large numbers of custom probe sets. 

Simple Robust Protocols

HCR v3.0 protocols are simple, robust, and exceptionally versatile, enabling multiplexed quantitative RNA analyses in diverse organisms, sample types, and assay formats. Learn more 

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Straightforward Multiplexing

Orthogonal HCR amplifiers enable 1-step signal amplification for up to 5 target RNAs simultaneously. Learn more

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Automatic Background Suppression

HCR v3.0 probes and amplifiers provide automatic background suppression throughout the protocol, dramatically enhancing performance and ease-of-use. Learn more