Custom Probe Design
HCR v3.0 probe sets enable multiplexed quantitative RNA fluorescence in situ hybridization (RNA-FISH), RNA flow cytometry, and northern blotting. Learn more
If your target is not already in our catalog, the Molecular Instruments Team will be pleased to design a custom probe set for any target mRNA in any organism across the tree of life. View gallery

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Custom Ordering
Please provide the accession number (if available) or the target RNA sequence (including 5' and 3' UTRs) when you place the order.
Rapid Worldwide Delivery
Upon receipt of a valid purchase order, we aim to ship custom probe sets within 5 business days.
Volume Discounts
Volume discounts are available when ordering large numbers of custom probe sets.
Simple Robust Protocols
HCR v3.0 protocols are simple, robust, and exceptionally versatile, enabling multiplexed quantitative RNA analyses in diverse organisms, sample types, and assay formats. Learn more
Straightforward Multiplexing
Orthogonal HCR amplifiers enable 1-step signal amplification for up to 5 target RNAs simultaneously. Learn more
Automatic Background Suppression
HCR v3.0 probes and amplifiers provide automatic background suppression throughout the protocol, dramatically enhancing performance and ease-of-use. Learn more
Custom Probe Design
✓ Any target mRNA in any organism
✓ Straightforward multiplexing
✓ Automatic background suppression
✓ Rapid worldwide delivery